Pd-tBuONO Cocatalyzed Aerobic Indole Synthesis

Xiao Shan Ning, Xin Liang, Kang Fei Hu, Chuan Zhi Yao, Jian Ping Qu, Yan Biao Kang

科研成果: 期刊稿件文章同行评审

35 引用 (Scopus)

摘要

A Pd-tBuONO co-catalyzed scalable and practical synthesis of indoles with molecular oxygen as terminal oxidant is developed. Either terminal or internal 2-vinylanilines could be smoothly converted to desired indoles under one general condition. This method has been evaluated in the large scale synthesis of indomethacin and a potential anti-breast cancer drug candidate 1. (Figure presented.).

源语言英语
页(从-至)1590-1594
页数5
期刊Advanced Synthesis and Catalysis
360
8
DOI
出版状态已出版 - 17 4月 2018

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