TY - JOUR
T1 - Progress of succinic acid production from renewable resources
T2 - Metabolic and fermentative strategies
AU - Jiang, Min
AU - Ma, Jiangfeng
AU - Wu, Mingke
AU - Liu, Rongming
AU - Liang, Liya
AU - Xin, Fengxue
AU - Zhang, Wenming
AU - Jia, Honghua
AU - Dong, Weiliang
N1 - Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2017/12
Y1 - 2017/12
N2 - Succinic acid is a four-carbon dicarboxylic acid, which has attracted much interest due to its abroad usage as a precursor of many industrially important chemicals in the food, chemicals, and pharmaceutical industries. Facing the shortage of crude oil supply and demand of sustainable development, biological production of succinic acid from renewable resources has become a topic of worldwide interest. In recent decades, robust producing strain selection, metabolic engineering of model strains, and process optimization for succinic acid production have been developed. This review provides an overview of succinic acid producers and cultivation technology, highlight some of the successful metabolic engineering approaches.
AB - Succinic acid is a four-carbon dicarboxylic acid, which has attracted much interest due to its abroad usage as a precursor of many industrially important chemicals in the food, chemicals, and pharmaceutical industries. Facing the shortage of crude oil supply and demand of sustainable development, biological production of succinic acid from renewable resources has become a topic of worldwide interest. In recent decades, robust producing strain selection, metabolic engineering of model strains, and process optimization for succinic acid production have been developed. This review provides an overview of succinic acid producers and cultivation technology, highlight some of the successful metabolic engineering approaches.
KW - Carbon dioxide
KW - Metabolic engineering
KW - NADH/NAD
KW - Renewable resources
KW - Succinic acid
UR - http://www.scopus.com/inward/record.url?scp=85020709736&partnerID=8YFLogxK
U2 - 10.1016/j.biortech.2017.05.209
DO - 10.1016/j.biortech.2017.05.209
M3 - 文献综述
C2 - 28622981
AN - SCOPUS:85020709736
SN - 0960-8524
VL - 245
SP - 1710
EP - 1717
JO - Bioresource Technology
JF - Bioresource Technology
ER -
