Radical-mediated diamination of alkenes with phenylhydrazine and azodicarboxylates: Highly diastereoselective synthesis of trans-diamines from cycloalkenes

Ming Kui Zhu, Yu Chen Chen, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

59 引用 (Scopus)

摘要

Metal-free synthesis: Diamination of alkenes by using phenylhydrazine and azodicarboxylates could be achieved in a one-pot manner under very mild conditions (see scheme; Boc=tert-butoxycarbonyl). This process works with the assistance of acetic acid by means of a radical mechanism and displays a high trans selectivity when cycloalkene substrates were used in the reaction.

源语言英语
页(从-至)5250-5254
页数5
期刊Chemistry - A European Journal
19
17
DOI
出版状态已出版 - 22 4月 2013
已对外发布

指纹

探究 'Radical-mediated diamination of alkenes with phenylhydrazine and azodicarboxylates: Highly diastereoselective synthesis of trans-diamines from cycloalkenes' 的科研主题。它们共同构成独一无二的指纹。

引用此