Recent advances in perovskite oxides for non-enzymatic electrochemical sensors: A review

Non-enzymatic electrochemical sensors with significant advantages of high sensitivity, long-term stability, and excellent reproducibility, are one promising technology to solve many challenges, such as the detection of toxic substances and viruses. Among various materials, perovskite oxides have become a promising candidate for use in non-enzymatic electrochemical sensors because of their low cost, flexible structure, and high intrinsic catalytic activity. A comprehensive overview of the recent advances in perovskite oxides for non-enzymatic electrochemical sensors is provided, which includes the synthesis methods of nanostructured perovskites and the electrocatalytic mechanisms of perovskite catalysts. The better sensing performance of perovskite oxides is mainly due to the lattice O vacancies and superoxide oxygen ions (O₂²⁻/O⁻), which are generated by the transfer of lattice oxygen to adsorbed –OH and have performed excellent properties suitable for electrooxidation of analytes. However, the limited electron transfer kinetics, stability, and selectivity of perovskite oxides alone make perovskite oxides far from ready for scientific development. Therefore, composites of perovskite oxides with other materials like graphitic carbon, metals, metal compounds, conducting organics, and biomolecules are summarized. Furthermore, a brief section describing the future challenges and the corresponding recommendation is presented in this review.