Regioselective iodoamination of terminal ynamides for the synthesis of α-amino-β,β-diiodo-enamides

Hai Huang, Luning Tang, Xiaobo Han, Guangke He, Yang Xi, Hongjun Zhu

科研成果: 期刊稿件文章同行评审

26 引用 (Scopus)

摘要

A mild and efficient methodology involving the I2/TBHP-mediated intermolecular iodoamination of ynamides with amines for the synthesis of α-amino-β,β-diiodo-enamides was developed. This reaction provides the first intermolecular iodoamination of terminal alkynes to diiodo-enamines and can be easily applied to a wide range of substrates.

源语言英语
页(从-至)4321-4324
页数4
期刊Chemical Communications
52
23
DOI
出版状态已出版 - 2016

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