Selectfluor™-catalyzed oxidative cyclization of ynamides enables facile synthesis of oxazolidine-2,4-diones

Guangke He, Yuan Li, Zilun Yu, Zhaoqiang Chen, Yongming Tang, Guangliang Song, Teck Peng Loh

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17 引用 (Scopus)

摘要

A Selectfluor™-catalyzed oxidative cyclization of ynamides affording oxazolidine-2,4-diones in yields from 69%-94% is described. The reaction is run under air and exhibits excellent chemo-selectivity and functional group compatibility. Preliminary mechanistic studies reveal that the solvent DMSO acts as an oxidant, and the redox reaction of Selectfluor™ with DMSO generates the real active catalyst HBF4in situ.

源语言英语
页(从-至)3644-3648
页数5
期刊Organic Chemistry Frontiers
6
21
DOI
出版状态已出版 - 7 11月 2019

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