Synthesis of Alkyl Indium Reagents by Using Unactivated Alkyl Chlorides and Their Applications in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides

Bing Zhi Chen, Man Ling Zhi, Chuang Xin Wang, Xue Qiang Chu, Zhi Liang Shen, Teck Peng Loh

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摘要

An efficient method for the preparation of alkyl indium reagents by using unactivated and cheap alkyl chlorides as substrates in the presence of indium and LiI was developed. The thus-formed alkyl indium species effectively underwent palladium-catalyzed cross-coupling reactions with aryl halides with wide functional group tolerance.

源语言英语
页(从-至)1902-1905
页数4
期刊Organic Letters
20
7
DOI
出版状态已出版 - 6 4月 2018

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