TY - JOUR
T1 - Tandem, Effective Continuous Flow Process for the Epoxidation of Cyclohexene
AU - He, Wei
AU - Fang, Zheng
AU - Tian, Qitao
AU - Shen, Weidong
AU - Guo, Kai
N1 - Publisher Copyright:
© 2016 American Chemical Society.
PY - 2016/2/10
Y1 - 2016/2/10
N2 - In this study, a novel protocol consisting of peroxidatic reaction and epoxidation process was developed. Besides, a specific continuous extraction apparatus was also employed in the continuous flow synthesis process. Without additional purification, m-chloroperbenzoic acid (m-CPBA) generated in situ could react with cyclohexene, leading to high quality cyclohexene oxide. In the first stage, m-CPBA was obtained within a few seconds at room temperature by reacting m-chlorobenzoyl chloride with hydrogen peroxide, while cyclohexene oxide was prepared at 30 °C for 10 min in the following stage.
AB - In this study, a novel protocol consisting of peroxidatic reaction and epoxidation process was developed. Besides, a specific continuous extraction apparatus was also employed in the continuous flow synthesis process. Without additional purification, m-chloroperbenzoic acid (m-CPBA) generated in situ could react with cyclohexene, leading to high quality cyclohexene oxide. In the first stage, m-CPBA was obtained within a few seconds at room temperature by reacting m-chlorobenzoyl chloride with hydrogen peroxide, while cyclohexene oxide was prepared at 30 °C for 10 min in the following stage.
UR - http://www.scopus.com/inward/record.url?scp=84958225611&partnerID=8YFLogxK
U2 - 10.1021/acs.iecr.5b04187
DO - 10.1021/acs.iecr.5b04187
M3 - 文章
AN - SCOPUS:84958225611
SN - 0888-5885
VL - 55
SP - 1373
EP - 1379
JO - Industrial and Engineering Chemistry Research
JF - Industrial and Engineering Chemistry Research
IS - 5
ER -