摘要
The theoretically determined molecular structures of N-protonated 1,3,4,6 methyl-substituted 4-(m-OH phenyl) piperidines are correlated to their experimentally derived analgesic activities. It is concluded that the orientation of the 3-methyl group plays a crucial role in determining agonism and antagonism.
| 源语言 | 英语 |
|---|---|
| 页（从-至） | 53-56 |
| 页数 | 4 |
| 期刊 | NIDA research monograph |
| 卷 | 75 |
| 出版状态 | 已出版 - 1986 |
| 已对外发布 | 是 |