An environmentally friendly procedure for Mukaiyama aldol and Mukaiyama-Michael reactions using a catalytic amount of DBU under solvent- and metal-free conditions

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Abstract

Mukaiyama aldol and Mukaiyama-Michael reactions can proceed smoothly in the presence of a catalytic amount of DBU (20% mmol), to afford the corresponding products in moderate to good yields. This solvent- and metal-free approach provides an environmentally friendly procedure for Mukaiyama reactions.

Original languageEnglish
Pages (from-to)507-508
Number of pages2
JournalTetrahedron Letters
Volume46
Issue number3
DOIs
StatePublished - 17 Jan 2005
Externally publishedYes

Keywords

  • DBU
  • Metal-free
  • Mukaiyama reaction
  • Organic catalyst
  • Solvent-free condition

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