An inorganic iodine-catalyzed oxidative system for the synthesis of benzimidazoles using hydrogen peroxide under ambient conditions

Chenjie Zhu; Yunyang Wei

doi:10.1002/cssc.201100228

An inorganic iodine-catalyzed oxidative system for the synthesis of benzimidazoles using hydrogen peroxide under ambient conditions

Chenjie Zhu, Yunyang Wei

Nanjing University of Science and Technology

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

A simple and efficient catalytic oxidative system for the synthesis of benzimidazole derivatives with H₂O₂ in the presence of catalytic amounts of Bu₄NI is developed. The formation of highly reactive iodine (III) intermediate [Bu₄N]⁺[IO ₂]^- is detected by ESI-MS for the first time, and a possible mechanism for the oxidation is proposed.

Original language	English
Pages (from-to)	1082-1086
Number of pages	5
Journal	ChemSusChem
Volume	4
Issue number	8
DOIs	https://doi.org/10.1002/cssc.201100228
State	Published - 22 Aug 2011
Externally published	Yes

Keywords

aldehydes
dehydrogenation
heterocycles
homogeneous catalysis
hypervalent compounds

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10.1002/cssc.201100228

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title = "An inorganic iodine-catalyzed oxidative system for the synthesis of benzimidazoles using hydrogen peroxide under ambient conditions",

abstract = "A simple and efficient catalytic oxidative system for the synthesis of benzimidazole derivatives with H2O2 in the presence of catalytic amounts of Bu4NI is developed. The formation of highly reactive iodine (III) intermediate [Bu4N]+[IO 2]- is detected by ESI-MS for the first time, and a possible mechanism for the oxidation is proposed.",

keywords = "aldehydes, dehydrogenation, heterocycles, homogeneous catalysis, hypervalent compounds",

author = "Chenjie Zhu and Yunyang Wei",

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AU - Zhu, Chenjie

AU - Wei, Yunyang

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N2 - A simple and efficient catalytic oxidative system for the synthesis of benzimidazole derivatives with H2O2 in the presence of catalytic amounts of Bu4NI is developed. The formation of highly reactive iodine (III) intermediate [Bu4N]+[IO 2]- is detected by ESI-MS for the first time, and a possible mechanism for the oxidation is proposed.

AB - A simple and efficient catalytic oxidative system for the synthesis of benzimidazole derivatives with H2O2 in the presence of catalytic amounts of Bu4NI is developed. The formation of highly reactive iodine (III) intermediate [Bu4N]+[IO 2]- is detected by ESI-MS for the first time, and a possible mechanism for the oxidation is proposed.

KW - aldehydes

KW - dehydrogenation

KW - heterocycles

KW - homogeneous catalysis

KW - hypervalent compounds

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DO - 10.1002/cssc.201100228

M3 - 文章

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EP - 1086

JO - ChemSusChem

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ER -

An inorganic iodine-catalyzed oxidative system for the synthesis of benzimidazoles using hydrogen peroxide under ambient conditions

Abstract

Keywords

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