Copper-catalyzed one-pot oxidative amidation between methylarenes and amines

Yuhang Yang, Jiajia Gu, Zheng Fang, Zhao Yang, Ping Wei, Kai Guo

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A new method for the direct one-pot oxidative amidation between methylarenes and amines catalyzed by copper has been developed. This method integrates methylarene oxidation and amide bond formation, which are usually accomplished separately, into a single operation. In addition, the reaction provides a relatively high yield and has a wide substrate scope. Moreover, the starting reagents are abundant and available in a convenient way at a cheaper price.

Original languageEnglish
Pages (from-to)22797-22801
Number of pages5
JournalRSC Advances
Volume7
Issue number37
DOIs
StatePublished - 2017

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