Detection of nicotinamide adenine dinucleotide (NADH) and ethanol at ZnO nanostructure modified electrode with low overpotential

Hong Yan Bai; Jian Chun Bao; Zhi Hui Dai; Ke Liu

Detection of nicotinamide adenine dinucleotide (NADH) and ethanol at ZnO nanostructure modified electrode with low overpotential

Hong Yan Bai, Jian Chun Bao, Zhi Hui Dai, Ke Liu

Nanjing Normal University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The good catalytic activity of ZnO nanomaterial to the oxidation of nicotinamide adenine dinucleotide (NADH) was described for biosensing application. Compared to a bare electrode, the modified electrode decreased the oxidation overpotential of NADH for 0.47 V, decreased the interferences and minimized the surface fouling. With alcohol dehydrogenase (ADH) as a model, the proposed biosensor showed rapid and sensitive amperometric responses to ethanol with acceptable preparation reproducibility and stability. Nano-ZnO provided an efficient matrix for development of NADH biosensors and the prepared electrode can be used not only to detect the concentration of NADH in a biochemical reaction, but also used as the potential matrix for the construction of dehydrogenases.

Original language	English
Pages (from-to)	1786-1790
Number of pages	5
Journal	Acta Chimica Sinica
Volume	66
Issue number	15
State	Published - 14 Aug 2008
Externally published	Yes

Keywords

Alcohol dehydrogenase
Biosensor
Electrocatalytic oxidation
Ethanol
NADH
ZnO

Cite this

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title = "Detection of nicotinamide adenine dinucleotide (NADH) and ethanol at ZnO nanostructure modified electrode with low overpotential",

abstract = "The good catalytic activity of ZnO nanomaterial to the oxidation of nicotinamide adenine dinucleotide (NADH) was described for biosensing application. Compared to a bare electrode, the modified electrode decreased the oxidation overpotential of NADH for 0.47 V, decreased the interferences and minimized the surface fouling. With alcohol dehydrogenase (ADH) as a model, the proposed biosensor showed rapid and sensitive amperometric responses to ethanol with acceptable preparation reproducibility and stability. Nano-ZnO provided an efficient matrix for development of NADH biosensors and the prepared electrode can be used not only to detect the concentration of NADH in a biochemical reaction, but also used as the potential matrix for the construction of dehydrogenases.",

keywords = "Alcohol dehydrogenase, Biosensor, Electrocatalytic oxidation, Ethanol, NADH, ZnO",

author = "Bai, {Hong Yan} and Bao, {Jian Chun} and Dai, {Zhi Hui} and Ke Liu",

year = "2008",

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volume = "66",

pages = "1786--1790",

journal = "Acta Chimica Sinica",

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T1 - Detection of nicotinamide adenine dinucleotide (NADH) and ethanol at ZnO nanostructure modified electrode with low overpotential

AU - Bai, Hong Yan

AU - Bao, Jian Chun

AU - Dai, Zhi Hui

AU - Liu, Ke

PY - 2008/8/14

Y1 - 2008/8/14

N2 - The good catalytic activity of ZnO nanomaterial to the oxidation of nicotinamide adenine dinucleotide (NADH) was described for biosensing application. Compared to a bare electrode, the modified electrode decreased the oxidation overpotential of NADH for 0.47 V, decreased the interferences and minimized the surface fouling. With alcohol dehydrogenase (ADH) as a model, the proposed biosensor showed rapid and sensitive amperometric responses to ethanol with acceptable preparation reproducibility and stability. Nano-ZnO provided an efficient matrix for development of NADH biosensors and the prepared electrode can be used not only to detect the concentration of NADH in a biochemical reaction, but also used as the potential matrix for the construction of dehydrogenases.

AB - The good catalytic activity of ZnO nanomaterial to the oxidation of nicotinamide adenine dinucleotide (NADH) was described for biosensing application. Compared to a bare electrode, the modified electrode decreased the oxidation overpotential of NADH for 0.47 V, decreased the interferences and minimized the surface fouling. With alcohol dehydrogenase (ADH) as a model, the proposed biosensor showed rapid and sensitive amperometric responses to ethanol with acceptable preparation reproducibility and stability. Nano-ZnO provided an efficient matrix for development of NADH biosensors and the prepared electrode can be used not only to detect the concentration of NADH in a biochemical reaction, but also used as the potential matrix for the construction of dehydrogenases.

KW - Alcohol dehydrogenase

KW - Biosensor

KW - Electrocatalytic oxidation

KW - Ethanol

KW - NADH

KW - ZnO

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M3 - 文章

AN - SCOPUS:84880833698

SN - 0567-7351

VL - 66

SP - 1786

EP - 1790

JO - Acta Chimica Sinica

JF - Acta Chimica Sinica

IS - 15

ER -

Detection of nicotinamide adenine dinucleotide (NADH) and ethanol at ZnO nanostructure modified electrode with low overpotential

Abstract

Keywords

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