Efficient FeIII-catalyzed synthesis of bis(indolyl)methanes in ionic liquids

Shun Jun Ji, Min Feng Zhou, Da Gong Gu, Zhao Qin Jiang, Teck Peng Loh

Research output: Contribution to journalArticlepeer-review

209 Scopus citations

Abstract

An efficient synthesis of bis(indolyl)methanes through Fe III-catalyzed electrophilic substitution reactions of indoles with various aldehydes in ionic liquid is described. It was found that the ionic liquids involving FeCl3·6H2O were the most efficient catalytic systems, and could be simply recycled without significant loss of activity.

Original languageEnglish
Pages (from-to)1584-1587
Number of pages4
JournalEuropean Journal of Organic Chemistry
Issue number7
DOIs
StatePublished - 26 Mar 2004
Externally publishedYes

Keywords

  • Bis(indolyl)methanes
  • Indoles
  • Ionic liquids
  • Iron

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