Highly sensitive "signal-on" electrochemiluminescent biosensor for the detection of DNA based on dual quenching and strand displacement reaction

Jing Lou, Zhaoyin Wang, Xiao Wang, Jianchun Bao, Wenwen Tu, Zhihui Dai

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A "signal-on" electrochemiluminescent DNA biosensing platform was proposed based on the dual quenching and strand displacement reaction. This novel "signal-on" detection strategy revealed its sensitivity in achieving a detection limit of 2.4 aM and its selectivity in distinguishing single nucleotide polymorphism of target DNA.

Original languageEnglish
Pages (from-to)14578-14581
Number of pages4
JournalChemical Communications
Volume51
Issue number78
DOIs
StatePublished - 10 Aug 2015
Externally publishedYes

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