Hydrazine as facile nitrogen source for direct synthesis of amines over a supported Pt catalyst

Jing Wang, Sen Ye, Xiang Liu, Teck Peng Loh

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Facile preparation of secondary amines from alcohols or aldehydes is achieved by using the hydrazine (N2H4) as an easy-to-handle nitrogen source. The anatase titania-supported Pt (Pt/TiO2-A) is discovered to be an efficient catalyst to enable the first alcohols/aldehydes to amines conversion with N2H4 as the only nitrogen and hydrogen source without any additional base or additives. Mechanistic studies suggest that this alcohol-to-amine transformation proceeds by the sequential alcohol dehydrogenation, aldehyde-N2H4 condensation, azine reduction, imine formation, and reduction processes in one pot. As N2H4 is a strong nucleophile that readily reacts with aldehyde, the unique catalytic property of Pt/TiO2-A ensures the high selectivity of amine products by providing multifunctional active sites for dehydrogenation and multiple reductions. This study highlights the considerable potential of hydrazine in direct synthesis of nitrogen-containing fine chemicals with a fine-tuned heterogeneous Pt catalyst, which is safe, green, and easy to handle.

Original languageEnglish
Pages (from-to)16283-16295
Number of pages13
JournalACS Sustainable Chemistry and Engineering
Volume8
Issue number43
DOIs
StatePublished - 2 Nov 2020

Keywords

  • Alcohols
  • Aldehydes
  • Heterogeneous catalysis
  • Hydrazine
  • Secondary amines
  • Supported Pt catalyst

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