Abstract
A regular nanostructure has been widely confirmed to result ina marked improvement in material performance in biosensing applications. In the present study, a regular nanostructured Prussian blue (PB) film with two heterogeneous crystal layers was synthesized in-situ using a secondary growth method. A PB seed layer was first controlled to form uniform cube-like crystal nuclei through an ultrasonic reaction with a single reactant. Then, well-defined 100 nm PB nanocubes were further crystallized on this seed layer using a self-assembly approach. In order to accelerate the electron transfer rate during the enzyme reaction for glucose detection, the graphene was used as the main cross-linker to immobilize glucose oxidase on the PB film. The as-prepared biosensor exhibited high electrocatalysis and electron conductivity for the detection of trace glucose with a sensitivity of 141.5 μA mM−1 cm−2, as well as excellent anti-interference ability in the presence of ascorbic acid and uric acid under a low operation potential of −0.05 V.
Original language | English |
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Pages (from-to) | 297-302 |
Number of pages | 6 |
Journal | Progress in Natural Science: Materials International |
Volume | 27 |
Issue number | 3 |
DOIs | |
State | Published - Jun 2017 |
Keywords
- Biosensors
- Electrochemistry
- In-situ secondary growth
- Prussian blue film
- Regular nanostructure