In-situ secondary growth of nanocube-based Prussian-blue film as an ultrasensitive biosensor

Yu Liu, Jingmeng Peng, Danfeng Jiang, Zhenyu Chu, Wanqin Jin

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A regular nanostructure has been widely confirmed to result ina marked improvement in material performance in biosensing applications. In the present study, a regular nanostructured Prussian blue (PB) film with two heterogeneous crystal layers was synthesized in-situ using a secondary growth method. A PB seed layer was first controlled to form uniform cube-like crystal nuclei through an ultrasonic reaction with a single reactant. Then, well-defined 100 nm PB nanocubes were further crystallized on this seed layer using a self-assembly approach. In order to accelerate the electron transfer rate during the enzyme reaction for glucose detection, the graphene was used as the main cross-linker to immobilize glucose oxidase on the PB film. The as-prepared biosensor exhibited high electrocatalysis and electron conductivity for the detection of trace glucose with a sensitivity of 141.5 μA mM−1 cm−2, as well as excellent anti-interference ability in the presence of ascorbic acid and uric acid under a low operation potential of −0.05 V.

Original languageEnglish
Pages (from-to)297-302
Number of pages6
JournalProgress in Natural Science: Materials International
Volume27
Issue number3
DOIs
StatePublished - Jun 2017

Keywords

  • Biosensors
  • Electrochemistry
  • In-situ secondary growth
  • Prussian blue film
  • Regular nanostructure

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