Light-controlled nanocarriers for drug release

Zhaocui Gong, Chao Yin, Hui Zhao, Xiaomei Lu, Quli Fan, Wei Huang

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

The study of light-responsive nanocarriers is becoming one of the hottest topics in biomedical field due to their precise control of drug release for cancer therapy in spatiotemporal level. This contribution systematically reviewed three mechanisms for controlled drug release of photosensitive nanocarriers, including (1) photoisomerization caused morphological transformation of nanocarriers, (2) photoreaction caused degradation of nanocarriers, and (3) photothermal caused disruption of nanocarriers. This review briefly introduced the three mechanisms and their corresponding photosensitive materials. In addition, the recent research developments and problems remained of photosensitive materials for drug delivery and controlled release were pointed out. This review also provided useful references for photosensitive nanocarriers in biological applications and the research prospects were further proposed.

Original languageEnglish
Pages (from-to)1387-1396
Number of pages10
JournalProgress in Chemistry
Volume28
Issue number9
DOIs
StatePublished - 24 Sep 2016

Keywords

  • Cancer therapy
  • Controlled drug release
  • Photosensitive nanocarriers

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