TY - JOUR
T1 - Low coordinate germanium(II) and tin(II) hydride complexes
T2 - Efficient catalysts for the hydroboration of carbonyl compounds
AU - Hadlington, Terrance J.
AU - Hermann, Markus
AU - Frenking, Gernot
AU - Jones, Cameron
PY - 2014/2/26
Y1 - 2014/2/26
N2 - This study details the first use of well-defined low-valent p-block metal hydrides as catalysts in organic synthesis. That is, the bulky, two-coordinate germanium(II) and tin(II) hydride complexes, L†(H)M: (M = Ge or Sn, L† = -N(Ar†)(SiPri 3), Ar† = C6H2{C(H)Ph 2}2Pri-2,6,4), are shown to act as efficient catalysts for the hydroboration (with HBpin, pin = pinacolato) of a variety of unactivated, and sometimes very bulky, carbonyl compounds. Catalyst loadings as low as 0.05 mol % are required to achieve quantitative conversions, with turnover frequencies in excess of 13 300 h-1 in some cases. This activity rivals that of currently available catalysts used for such reactions.
AB - This study details the first use of well-defined low-valent p-block metal hydrides as catalysts in organic synthesis. That is, the bulky, two-coordinate germanium(II) and tin(II) hydride complexes, L†(H)M: (M = Ge or Sn, L† = -N(Ar†)(SiPri 3), Ar† = C6H2{C(H)Ph 2}2Pri-2,6,4), are shown to act as efficient catalysts for the hydroboration (with HBpin, pin = pinacolato) of a variety of unactivated, and sometimes very bulky, carbonyl compounds. Catalyst loadings as low as 0.05 mol % are required to achieve quantitative conversions, with turnover frequencies in excess of 13 300 h-1 in some cases. This activity rivals that of currently available catalysts used for such reactions.
UR - http://www.scopus.com/inward/record.url?scp=84896867597&partnerID=8YFLogxK
U2 - 10.1021/ja5006477
DO - 10.1021/ja5006477
M3 - 文章
AN - SCOPUS:84896867597
SN - 0002-7863
VL - 136
SP - 3028
EP - 3031
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 8
ER -