Microwave-assisted gewald synthesis of 2-amimothio-phenes using functional ionic liquid as soluble support

Yi Hu, Ping Wei, He Huang, Shi Qing Han, Ping Kai Ouyang

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

A microwave-assisted liquid-phase Gewald synthesis of 2-aminothiophenes was developed using task-specific ionic liquid - [2-hydemim][BF4] as soluble support. This new synthetic method is simple and efficient, and the products are obtained in good to excellent yields with high purities, without the need for chromatographic purification.

Original languageEnglish
Pages (from-to)375-380
Number of pages6
JournalHeterocycles
Volume68
Issue number2
DOIs
StatePublished - 1 Feb 2006

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