Organocatalytic synthesis of highly functionalized pyridines at room temperature

Zugui Shi; Teck Peng Loh

doi:10.1002/anie.201301519

Organocatalytic synthesis of highly functionalized pyridines at room temperature

Zugui Shi, Teck Peng Loh

Research output: Contribution to journal › Article › peer-review

75 Scopus citations

Abstract

Amines by all means: A unique aza-Rauhut-Currier/cyclization/desulfonation cascade reaction between allenoates and N-sulfonyl-1-aza-1,3-dienes, catalyzed by the readily available diamine TMEDA, has been developed. This strategy provides facile access to a broad range of valuable highly functionalized pyridines in good yields under very mild reaction conditions.

Original language	English
Pages (from-to)	8584-8587
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	33
DOIs	https://doi.org/10.1002/anie.201301519
State	Published - 12 Aug 2013
Externally published	Yes

Keywords

amines
cyclization
heterocycles
organocatalysis
synthetic methods

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10.1002/anie.201301519

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abstract = "Amines by all means: A unique aza-Rauhut-Currier/cyclization/desulfonation cascade reaction between allenoates and N-sulfonyl-1-aza-1,3-dienes, catalyzed by the readily available diamine TMEDA, has been developed. This strategy provides facile access to a broad range of valuable highly functionalized pyridines in good yields under very mild reaction conditions.",

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author = "Zugui Shi and Loh, {Teck Peng}",

year = "2013",

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AU - Loh, Teck Peng

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KW - amines

KW - cyclization

KW - heterocycles

KW - organocatalysis

KW - synthetic methods

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M3 - 文章

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AN - SCOPUS:84882326625

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JO - Angewandte Chemie - International Edition

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IS - 33

ER -

Organocatalytic synthesis of highly functionalized pyridines at room temperature

Abstract

Keywords

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