Porous silicon nitride for scaffold material by direct forming with protective gelling

Muyi Shen, Huifen Zhao, Weiwei Feng, Yali Luo, Han Chen, Yifeng Zheng, Lin Ge, Lucun Guo

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Porous Si3N4 substrate for scaffold is prepared by the direct foaming process that is modified by introducing a protective gelling agent (PGA) combined with quench-freezing technique in this work. Nano-hydroxyapatite (nHA) is deposited onto the as-prepared substrate. The adhesion strength of the deposited nHA is evaluated with ultrasonic vibration method and the bioactivity of the pristine porous silicon nitride and that with nHA coating (nHA-coated Si3N4) are assessed by simulated body fluid (SBF) treatment along with in vitro cell culture experiments. The results indicate that compared with conventional direct foaming method, the introducing of PGA combined with quench-freezing significantly enhances the stability of foams and lowers the standard deviation of pore size distribution, leading to improved strength and reliability of the porous Si3N4 substrates. It is also found that the adhesion strength of the nHA coating is relatively low as shown by mass loss experiment with an ultrasonic cleaning device. The results of SBF treatment and in vitro cell culture experiment demonstrate that the pristine porous silicon nitride exhibits considerable bioactivity comparable to that with nHA coating.

Original languageEnglish
Pages (from-to)29342-29354
Number of pages13
JournalCeramics International
Volume47
Issue number20
DOIs
StatePublished - 15 Oct 2021

Keywords

  • Bioactivity
  • Nano-hydroxyapatite coating
  • Porous silicon nitride
  • Porous structure
  • Protective gelling agent

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