Rhodamine based turn-on fluorescent sensor for Hg2+ and its application of microfluidic system and bioimaging

Chuantao Liu; Ting Xiao; Yuchen Wang; Fang Wang; Xiaoqiang Chen

doi:10.1016/j.tet.2017.07.012

Rhodamine based turn-on fluorescent sensor for Hg²⁺ and its application of microfluidic system and bioimaging

Chuantao Liu, Ting Xiao, Yuchen Wang, Fang Wang, Xiaoqiang Chen

College of Chemical Engineering

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

In this paper, a new rhodamine derivative bearing thiazole and thiocarbonyl moieties 1 was synthesized and its sensing behaviors toward various metal ions were investigated by fluorescence spectroscopies and UV/Vis. The ring-opening process of spirolactam enables the selective fluorescence enhancement and colorimetric change for Hg²⁺ in CH₃CN-HEPES buffer (0.01 M, pH 7.4) (3:7, v/v). The selectivity and sensitivity of 1 towards Hg²⁺ lead to sensor 1 applied to microfluidic device and even used to functions Hg²⁺ sensing in Hela cells.

Original language	English
Pages (from-to)	5189-5193
Number of pages	5
Journal	Tetrahedron
Volume	73
Issue number	34
DOIs	https://doi.org/10.1016/j.tet.2017.07.012
State	Published - 2017

Keywords

Colorimetric sensor
Fluorescent sensor
Mercury ion
Microfluidic system
Rhodamine

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10.1016/j.tet.2017.07.012

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title = "Rhodamine based turn-on fluorescent sensor for Hg2+ and its application of microfluidic system and bioimaging",

abstract = "In this paper, a new rhodamine derivative bearing thiazole and thiocarbonyl moieties 1 was synthesized and its sensing behaviors toward various metal ions were investigated by fluorescence spectroscopies and UV/Vis. The ring-opening process of spirolactam enables the selective fluorescence enhancement and colorimetric change for Hg2+ in CH3CN-HEPES buffer (0.01 M, pH 7.4) (3:7, v/v). The selectivity and sensitivity of 1 towards Hg2+ lead to sensor 1 applied to microfluidic device and even used to functions Hg2+ sensing in Hela cells.",

keywords = "Colorimetric sensor, Fluorescent sensor, Mercury ion, Microfluidic system, Rhodamine",

author = "Chuantao Liu and Ting Xiao and Yuchen Wang and Fang Wang and Xiaoqiang Chen",

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T1 - Rhodamine based turn-on fluorescent sensor for Hg2+ and its application of microfluidic system and bioimaging

AU - Liu, Chuantao

AU - Xiao, Ting

AU - Wang, Yuchen

AU - Wang, Fang

AU - Chen, Xiaoqiang

PY - 2017

Y1 - 2017

N2 - In this paper, a new rhodamine derivative bearing thiazole and thiocarbonyl moieties 1 was synthesized and its sensing behaviors toward various metal ions were investigated by fluorescence spectroscopies and UV/Vis. The ring-opening process of spirolactam enables the selective fluorescence enhancement and colorimetric change for Hg2+ in CH3CN-HEPES buffer (0.01 M, pH 7.4) (3:7, v/v). The selectivity and sensitivity of 1 towards Hg2+ lead to sensor 1 applied to microfluidic device and even used to functions Hg2+ sensing in Hela cells.

AB - In this paper, a new rhodamine derivative bearing thiazole and thiocarbonyl moieties 1 was synthesized and its sensing behaviors toward various metal ions were investigated by fluorescence spectroscopies and UV/Vis. The ring-opening process of spirolactam enables the selective fluorescence enhancement and colorimetric change for Hg2+ in CH3CN-HEPES buffer (0.01 M, pH 7.4) (3:7, v/v). The selectivity and sensitivity of 1 towards Hg2+ lead to sensor 1 applied to microfluidic device and even used to functions Hg2+ sensing in Hela cells.

KW - Colorimetric sensor

KW - Fluorescent sensor

KW - Mercury ion

KW - Microfluidic system

KW - Rhodamine

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DO - 10.1016/j.tet.2017.07.012

M3 - 文章

AN - SCOPUS:85023190492

SN - 0040-4020

VL - 73

SP - 5189

EP - 5193

JO - Tetrahedron

JF - Tetrahedron

IS - 34

ER -

Rhodamine based turn-on fluorescent sensor for Hg²⁺ and its application of microfluidic system and bioimaging

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Keywords

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