Specific self-monitoring of metal-associated amyloid-β peptide disaggregation by a fluorescent chelator

Tao Yang, Xiaohui Wang, Changli Zhang, Xiang Ma, Kun Wang, Yanqing Wang, Jian Luo, Liu Yang, Cheng Yao, Xiaoyong Wang

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

A dual-functional fluorescent chelator can specifically target and disassemble metal-associated Aβ aggregates and simultaneously self-monitor the disaggregation by fluorescence in brain homogenates of mice with Alzheimer's disease.

Original languageEnglish
Pages (from-to)2245-2248
Number of pages4
JournalChemical Communications
Volume52
Issue number11
DOIs
StatePublished - 7 Feb 2016

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