Surface characteristics and hemocompatibility of modified NiTi alloy intravascular stents

Yaru Ni, Hairong Huang, Chunhua Lu, Junkai Xue, Zongzi Xu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

TiO2, ZrO2 and titanium oxide in deficiency oxygen environment were used to modify the surface of biomedical NiTi stents. The coatings were prepared by vacuum deposition. The surface microstructures and characteristics, blood compatibility of the modified stents in simulated body fluids were assessed using scanning electron microscopy (SEM), hemolysis test, coagulation test and blood platelet adhesion test. The hemocompatiblity of the modified stents were all improved by layer coating. Enhancement of blood compatibility was believed to stem from the improved surface water affinity and hemolysis resistance of the layer, and titanium oxide in deficiency oxygen environment displayed better. This study indicated that layer coating was a promising effective modification method for improving the surface properties of biomedical NiTi alloy intravascular stents. As a coating materials, titanium oxide in deficiency oxygen environment was better than TiO2 and ZrO2.

Original languageEnglish
Title of host publicationMaterials Research
EditorsZhongwei Gu, Zhongwei Gu, Zhongwei Gu, Yafang Han, Yafang Han, Yafang Han, Fusheng Pan, Fusheng Pan, Fusheng Pan, Fusheng Pan, Fusheng Pan, Fusheng Pan, Xitao Wang, Xitao Wang, Xitao Wang, Duan Weng, Duan Weng, Duan Weng, Shaoxiong Zhou, Shaoxiong Zhou, Shaoxiong Zhou
PublisherTrans Tech Publications Ltd
Pages1082-1089
Number of pages8
ISBN (Print)9780878493401, 9780878493401, 9780878493401
DOIs
StatePublished - 2009
EventMRS International Materials Research Conference, IMRC 2008 - Chongqing, China
Duration: 9 Jun 200812 Jun 2008

Publication series

NameMaterials Science Forum
Volume610-613
ISSN (Print)0255-5476
ISSN (Electronic)1662-9752

Conference

ConferenceMRS International Materials Research Conference, IMRC 2008
Country/TerritoryChina
CityChongqing
Period9/06/0812/06/08

Keywords

  • Hemocompatibility
  • Surface modification
  • TiO
  • ZrO

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