Synthesis and crystal structural characterization of two new 3,5-disubstituted 4-amino-1,2,4- triazoles

Xin He, Bin Li, Lang Chen, Xuan Shen, Dun Ru Zhu

Research output: Contribution to journalArticlepeer-review

Abstract

Two new asymmetrical 3-(p-R-phenyl)-4-amino- 5-(2-pyridyl)-1,2,4-triazoles (3a, R = CH3 and 3b, R = OCH3) were synthesized with a yield of 58% and 69%, respectively. The compounds 3a and 3b were characterized with FT-IR, 1H NMR, ESI-MS spectra, and elemental analysis. Additionally, their molecular and crystal structures were determined by single crystal X-ray analysis.

Original languageEnglish
Pages (from-to)201-206
Number of pages6
JournalHeterocyclic Communications
Volume20
Issue number4
DOIs
StatePublished - 2014

Keywords

  • 4-amino-1 2 4-triazole
  • Crystal structure
  • Hydrazine
  • Synthesis

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