Synthesis of 2-aminothiophenes on ionic liquid phase support using the Gewald reaction

Yi Hu, Ping Wei, He Huang, Shi Qing Han, Ping Kai Ouyang

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

The first report of the use of task-specific ionic liquid as soluble support for the Gewald synthesis of 2-aminothiophenes is reported in this article. This synthetic method is simple and efficient, and the products are obtained in good to excellent yields with high purities, without the need for chromatographic purification.

Original languageEnglish
Pages (from-to)1543-1548
Number of pages6
JournalSynthetic Communications
Volume36
Issue number11
DOIs
StatePublished - 2006

Keywords

  • 2-Aminothiophene
  • Gewald synthesis
  • Ionic liquids
  • Soluble support

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