Synthetic studies toward the total synthesis of tedanolide: assembly of the C1-C23 carbon backbone

Chek Ming Wong; Teck Peng Loh

doi:10.1016/j.tetlet.2006.04.044

Synthetic studies toward the total synthesis of tedanolide: assembly of the C1-C23 carbon backbone

Chek Ming Wong, Teck Peng Loh

Nanyang Technological University

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A stereoselective assembly of the C1-C23 fragment representing the carbon backbone of tedanolide was accomplished utilizing a chiral boron reagent to effect the aldol coupling of the C1-C12 diketoester fragment with the C13-C23 aldehyde fragment.

Original language	English
Pages (from-to)	4485-4489
Number of pages	5
Journal	Tetrahedron Letters
Volume	47
Issue number	26
DOIs	https://doi.org/10.1016/j.tetlet.2006.04.044
State	Published - 26 Jun 2006
Externally published	Yes

Keywords

Aldol
Boron reagent
Fragment assembly
Stereoselective
Tedanolide

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10.1016/j.tetlet.2006.04.044

Cite this

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title = "Synthetic studies toward the total synthesis of tedanolide: assembly of the C1-C23 carbon backbone",

abstract = "A stereoselective assembly of the C1-C23 fragment representing the carbon backbone of tedanolide was accomplished utilizing a chiral boron reagent to effect the aldol coupling of the C1-C12 diketoester fragment with the C13-C23 aldehyde fragment.",

keywords = "Aldol, Boron reagent, Fragment assembly, Stereoselective, Tedanolide",

author = "Wong, {Chek Ming} and Loh, {Teck Peng}",

year = "2006",

month = jun,

day = "26",

doi = "10.1016/j.tetlet.2006.04.044",

language = "英语",

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journal = "Tetrahedron Letters",

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T1 - Synthetic studies toward the total synthesis of tedanolide

T2 - assembly of the C1-C23 carbon backbone

AU - Wong, Chek Ming

AU - Loh, Teck Peng

PY - 2006/6/26

Y1 - 2006/6/26

N2 - A stereoselective assembly of the C1-C23 fragment representing the carbon backbone of tedanolide was accomplished utilizing a chiral boron reagent to effect the aldol coupling of the C1-C12 diketoester fragment with the C13-C23 aldehyde fragment.

AB - A stereoselective assembly of the C1-C23 fragment representing the carbon backbone of tedanolide was accomplished utilizing a chiral boron reagent to effect the aldol coupling of the C1-C12 diketoester fragment with the C13-C23 aldehyde fragment.

KW - Aldol

KW - Boron reagent

KW - Fragment assembly

KW - Stereoselective

KW - Tedanolide

UR - http://www.scopus.com/inward/record.url?scp=33646767486&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2006.04.044

DO - 10.1016/j.tetlet.2006.04.044

M3 - 文章

AN - SCOPUS:33646767486

SN - 0040-4039

VL - 47

SP - 4485

EP - 4489

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 26

ER -

Synthetic studies toward the total synthesis of tedanolide: assembly of the C1-C23 carbon backbone

Abstract

Keywords

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