A Ba/Pd catalytic system enables dehydrative cross-coupling and excellent E-selective wittig reactions

Peizhong Xie, Weishan Fu, Xinying Cai, Zuolian Sun, Ying Wu, Shuangshuang Li, Cuiqing Gao, Xiaobo Yang, Teck Peng Loh

科研成果: 期刊稿件文章同行评审

8 引用 (Scopus)

摘要

A Ba/Pd cooperative catalysis system was developed to enable the dehydrative cross-coupling of allylic alcohols with P-ylides to occur directly and promote a subsequent Wittig reaction in one pot. A variety of multisubstituted 1,4-dienes were isolated in good to excellent yields with broad P-ylides (stabilized by both ester and ketone carbonyl groups) and aldehyde (aliphatic and aromatic) substrates with excellent E selectivity.

源语言英语
页(从-至)7055-7059
页数5
期刊Organic Letters
21
17
DOI
出版状态已出版 - 6 9月 2019

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