A reusable microRNA sensor based on the electrocatalytic property of heteroduplexlated copper nanoclusters

Zhaoyin Wang; Ling Si; Jianchun Bao; Zhihui Dai

doi:10.1039/c5cc01081k

A reusable microRNA sensor based on the electrocatalytic property of heteroduplexlated copper nanoclusters

Zhaoyin Wang, Ling Si, Jianchun Bao, Zhihui Dai

Nanjing Normal University

科研成果: 期刊稿件 › 文章 › 同行评审

33 引用（Scopus）

摘要

DNA-RNA heteroduplexes have been used as templates for copper nanocluster (CuNC) formation for the first time. Taking advantage of the electrocatalysis of CuNCs, quantitation of miRNA can thus be accomplished. More importantly, by simply operating several rounds of CuNC formation, repeated detection of miRNA has further been realized, which is rare in miRNA biosensors.

源语言	英语
页（从-至）	6305-6307
页数	3
期刊	Chemical Communications
卷	51
期	29
DOI	https://doi.org/10.1039/c5cc01081k
出版状态	已出版 - 14 4月 2015
已对外发布	是

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AU - Si, Ling

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AU - Dai, Zhihui

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AB - DNA-RNA heteroduplexes have been used as templates for copper nanocluster (CuNC) formation for the first time. Taking advantage of the electrocatalysis of CuNCs, quantitation of miRNA can thus be accomplished. More importantly, by simply operating several rounds of CuNC formation, repeated detection of miRNA has further been realized, which is rare in miRNA biosensors.

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A reusable microRNA sensor based on the electrocatalytic property of heteroduplexlated copper nanoclusters

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