Asymmetric synthesis of C-aliphatic homoallylic amines and biologically important cyclohexenylamine analogues

Chi Lik Ken Lee; Hui Yvonne Ling; Teck Peng Loh

doi:10.1021/jo048903o

Asymmetric synthesis of C-aliphatic homoallylic amines and biologically important cyclohexenylamine analogues

Chi Lik Ken Lee, Hui Yvonne Ling, Teck Peng Loh

National University of Singapore

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33 引用（Scopus）

摘要

An efficient method for the asymmetric synthesis of C-aliphatic homoallylic amines with up to 94% yield and 80% de is reported. Ring-closing metathesis of several chiral homoallylic amines using the second-generation Grubbs catalyst provided easy access to a wide variety of cyclohexenylamines.

源语言	英语
页（从-至）	7787-7789
页数	3
期刊	Journal of Organic Chemistry
卷	69
期	22
DOI	https://doi.org/10.1021/jo048903o
出版状态	已出版 - 29 10月 2004
已对外发布	是

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10.1021/jo048903o

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abstract = "An efficient method for the asymmetric synthesis of C-aliphatic homoallylic amines with up to 94% yield and 80% de is reported. Ring-closing metathesis of several chiral homoallylic amines using the second-generation Grubbs catalyst provided easy access to a wide variety of cyclohexenylamines.",

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AB - An efficient method for the asymmetric synthesis of C-aliphatic homoallylic amines with up to 94% yield and 80% de is reported. Ring-closing metathesis of several chiral homoallylic amines using the second-generation Grubbs catalyst provided easy access to a wide variety of cyclohexenylamines.

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Asymmetric synthesis of C-aliphatic homoallylic amines and biologically important cyclohexenylamine analogues

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