Dehydrogenative Fluorination of gem-Difluoroalkenes to Access Multi-Substituted Trifluoromethylalkenes

Manman Wang, Mengyu Wu, Rui Ma, Kai Chen, Chuan Zhu, Chao Feng

科研成果: 期刊稿件文章同行评审

4 引用 (Scopus)

摘要

A dehydrogenative fluorination method is developed to access multi-substituted trifluoromethylalkenes starting from a variety of gem-difluoroalkenes. The reaction proceeds with electrophilic fluorination source NFSI only and accommodates a wide range of functional groups, thus complementing the previously reported protocols. Additionally, a visible-light-promoted stereoinversion is revealed to enable the access to E-isomer enriched products.

源语言英语
页(从-至)2416-2421
页数6
期刊Advanced Synthesis and Catalysis
365
14
DOI
出版状态已出版 - 18 7月 2023

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