Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent

Kok Ping Chan; Teck Peng Loh

doi:10.1016/j.tetlet.2004.09.049

Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent

Kok Ping Chan, Teck Peng Loh

National University of Singapore

科研成果: 期刊稿件 › 文章 › 同行评审

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摘要

A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products. A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products.

源语言	英语
页（从-至）	8387-8390
页数	4
期刊	Tetrahedron Letters
卷	45
期	45
DOI	https://doi.org/10.1016/j.tetlet.2004.09.049
出版状态	已出版 - 1 11月 2004
已对外发布	是

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title = "Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent",

abstract = "A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products. A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products.",

keywords = "In(OTf), InCl, Prins cyclization, Tetrahydropyran",

author = "Chan, {Kok Ping} and Loh, {Teck Peng}",

year = "2004",

month = nov,

day = "1",

doi = "10.1016/j.tetlet.2004.09.049",

language = "英语",

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T1 - Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent

AU - Chan, Kok Ping

AU - Loh, Teck Peng

PY - 2004/11/1

Y1 - 2004/11/1

N2 - A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products. A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products.

AB - A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products. A one-pot multi-component Lewis acid-catalyzed Prins cyclization was developed with high yield and selectivity. The crossed 2,4,6-trisubstituted tetrahydropyran products were formed with high stereoselectivity. This catalytic method could also be used with α,β-unsaturated aldehydes affording moderate yields of products.

KW - In(OTf)

KW - InCl

KW - Prins cyclization

KW - Tetrahydropyran

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DO - 10.1016/j.tetlet.2004.09.049

M3 - 文章

AN - SCOPUS:5144229083

SN - 0040-4039

VL - 45

SP - 8387

EP - 8390

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 45

ER -

Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent

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