Oxidative Thioesterification of Alkenes Mediated by 1,3-Dibromo-5,5-dimethylhydantoin and DMSO for the Synthesis of α-Ketothioesters

Jiawei Hua, Jiaqi Xu, Jia Xu, Bochao Zhou, Dong Zhang, Zhao Yang, Zheng Fang, Kai Guo

科研成果: 期刊稿件文章同行评审

10 引用 (Scopus)

摘要

A simple and mild approach for the synthesis of α-ketothioesters via 1,3-Dibromo-5,5-dimethylhydantoin (DBH)/DMSO mediated oxidative thioesterification of alkenes has been developed. Various of α-ketothioesters products were produced in moderate to good yields under metal-free conditions. And this method features readily available starting materials and broad substrate scope. Moreover, a plausible mechanism was proposed based on the methyl bromide captured experiment.

源语言英语
页(从-至)4056-4060
页数5
期刊European Journal of Organic Chemistry
2019
25
DOI
出版状态已出版 - 7 7月 2019

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