Photocatalytic Radical Cascade Dehalogenation/Carbo-cyclization/Sulfonylation Leading to Indole- and Benzofuran-Based Benzylic Sulfones

Qing Quan Liu, Jia Zhuo Li, Yan Jing Wang, Yan Ning Leng, Yu Wen Huang, Xin Chao Meng, Bo Rong Leng, De Cai Wang, Yi Long Zhu

科研成果: 期刊稿件文章同行评审

4 引用 (Scopus)

摘要

This study presents a convenient approach to the synthesis of indole- and benzofuran-based benzylic sulfones using unactivated alkynes containing aryl iodides and sodium sulfinates under visible light irradiation. The procedure involves a sequential series of dehalogenation, carbo-cyclization, and radical sulfonylation. Plausible insights into the reaction mechanism are derived from control experiments, leading to the proposal of a radical cascade reaction pathway.

源语言英语
页(从-至)17227-17236
页数10
期刊Journal of Organic Chemistry
88
24
DOI
出版状态已出版 - 15 12月 2023

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