TY - JOUR
T1 - Preparation of Active On-Demand Antibacterial Hydrogel Epidermis Electrodes Based on Flora Balance Strategy for Intelligent Prostheses
AU - Sun, Yifei
AU - Xiao, Mingxuan
AU - Tang, Zhenxuan
AU - Wu, Haibo
AU - Cheng, Siyuan
AU - Han, Xu
AU - Xu, Xiaolong
AU - Chen, Weikang
AU - Tao, Kai
AU - Zha, Baoli
AU - Huo, Fengwei
AU - Wu, Jin
AU - Xie, Ruijie
N1 - Publisher Copyright:
© 2025 American Chemical Society.
PY - 2025
Y1 - 2025
N2 - Hydrogel epidermis electrodes have demonstrated remarkable potential for stable electrophysiological signal acquisition in the field of intelligent prostheses. However, current hydrogel electrodes face challenges in providing on-demand antibacterial effects due to dynamic skin conditions, such as sweating, which may induce skin inflammation, thus limiting their practical applications. Herein, an active on-demand antibacterial hydrogel electrode is prepared by encapsulating Staphylococcus epidermidis (S. epidermidis) into the hydrogel electrode based on the strategy of flora balance. The encapsulated S. epidermidis metabolizes nutrients from sweat to produce antibacterial substances, achieving an 82% inhibition rate against Staphylococcus aureus over a 24-h period. With on-demand antibacterial properties, low interfacial impedance, and strong adhesion, the hydrogel electrode enables the acquisition of various high-quality electrophysiological signals with a signal-to-noise ratio of 22.2 dB after 12 h of attachment, much higher than that of commercial hydrogel electrodes. When combined with machine learning models to decode electromyographic signals, the electrode system achieves the high gesture recognition accuracy of 95%. Furthermore, the stable signal acquisition enabled by the antibacterial hydrogel electrode facilitates real-time wireless control of robotic hands, providing a robust technical platform for intelligent prosthetic applications.
AB - Hydrogel epidermis electrodes have demonstrated remarkable potential for stable electrophysiological signal acquisition in the field of intelligent prostheses. However, current hydrogel electrodes face challenges in providing on-demand antibacterial effects due to dynamic skin conditions, such as sweating, which may induce skin inflammation, thus limiting their practical applications. Herein, an active on-demand antibacterial hydrogel electrode is prepared by encapsulating Staphylococcus epidermidis (S. epidermidis) into the hydrogel electrode based on the strategy of flora balance. The encapsulated S. epidermidis metabolizes nutrients from sweat to produce antibacterial substances, achieving an 82% inhibition rate against Staphylococcus aureus over a 24-h period. With on-demand antibacterial properties, low interfacial impedance, and strong adhesion, the hydrogel electrode enables the acquisition of various high-quality electrophysiological signals with a signal-to-noise ratio of 22.2 dB after 12 h of attachment, much higher than that of commercial hydrogel electrodes. When combined with machine learning models to decode electromyographic signals, the electrode system achieves the high gesture recognition accuracy of 95%. Furthermore, the stable signal acquisition enabled by the antibacterial hydrogel electrode facilitates real-time wireless control of robotic hands, providing a robust technical platform for intelligent prosthetic applications.
KW - active on-demand antibacterial hydrogel
KW - flora balance strategy
KW - gesture recognition
KW - hydrogel epidermis electrode
KW - intelligent prostheses
UR - http://www.scopus.com/inward/record.url?scp=105005510936&partnerID=8YFLogxK
U2 - 10.1021/acsami.5c05452
DO - 10.1021/acsami.5c05452
M3 - 文章
AN - SCOPUS:105005510936
SN - 1944-8244
JO - ACS Applied Materials and Interfaces
JF - ACS Applied Materials and Interfaces
ER -