@article{1d5cc719ca6e48d8a574add79ed6f388,
title = "Regioselective Chlorination of Quinoline Derivatives via Fluorine Mediation in a Microfluidic Reactor",
abstract = "A novel green and efficient reaction route for the synthesis of 2-chloroquinoline via N-fluoride fluorinated by 1-Chloromethyl-4-fluoro-1,4-diazoniabicyclo [2.2.2] octane bis(tetrafluoroborate) (Selectfluor) with 1,3-Dichloro-5,5-dimethylhydantoin (DCDMH) in Vapourtec reactor has been developed. In addition, a series of C2 heterocyclic derivative products are obtained in moderate to good yields under no metal conditions.",
keywords = "C2 heterocycle, Halogenation, Microreactor, Nucleophilic substitution, Selectfluor",
author = "Hao Qi and Xin Li and Zhuang Liu and Miao, {Shan Shan} and Zheng Fang and Lin Chen and Zheng Fang and Kai Guo",
note = "Publisher Copyright: {\textcopyright} 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2018",
month = oct,
day = "17",
doi = "10.1002/slct.201802925",
language = "英语",
volume = "3",
pages = "10689--10693",
journal = "ChemistrySelect",
issn = "2365-6549",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "38",
}