Synthesis of benzofuro- And benzothieno[2,3-: C] pyridines via copper-catalyzed [4 + 2] annulation of ketoxime acetates with acetoacetanilide

Binsen Rong, Gaochen Xu, Huan Yan, Sai Zhang, Qinghuan Wu, Ning Zhu, Zheng Fang, Jindian Duan, Kai Guo

科研成果: 期刊稿件文章同行评审

21 引用 (Scopus)

摘要

An efficient copper-catalyzed annulation of ketoxime acetates with acetoacetanilide has been developed. This strategy provides an alternate route towards the synthesis of benzofuro- and benzothieno[2,3-c]pyridines with good functional group tolerance and operational simplicity. Mechanistic investigation indicates that an ionic pathway rather than a radical pathway was involved in the transformation.

源语言英语
页(从-至)2939-2943
页数5
期刊Organic Chemistry Frontiers
8
12
DOI
出版状态已出版 - 21 6月 2021

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