@article{86e1a404278b4dacbd404fdee68733d9,
title = "Synthesis of Benzofuro[3,2- c ]isoquinolines through Anionic Intramolecular Cyclization",
abstract = "Benzofuro[3,2- c ]isoquinolines are among the typical tetraheterocycles. The synthesis of benzofuro[3,2- c ]isoquinoline derivatives in the presence of a catalytic amount of KOH has been developed. A variety of substituents could be tolerated. The base (KOH) works as a catalyst. A gram-scale synthesis was performed. Control experiments confirmed that a cascade anionic annulation is involved rather than a radical cyclization.",
keywords = "base, benzofuro[3,2- c ]isoquinolines, cascade annulation, catalyst free, tetraheterocycles, transition-metal-free",
author = "Bo Yang and Dai, {Peng Fei} and Qu, {Jian Ping} and Kang, {Yan Biao}",
note = "Publisher Copyright: {\textcopyright} 2025. Thieme. All rights reserved.",
year = "2025",
doi = "10.1055/a-2591-8986",
language = "英语",
journal = "Synthesis (Germany)",
issn = "0039-7881",
publisher = "Georg Thieme Verlag",
}