Synthesis of Phenanthridinones by Palladium-Catalyzed Cyclization of N -Aryl-2-aminopyridines with 2-Iodobenzoic Acids in Water

Xiaojuan Ding, Lei Zhang, Yiyang Mao, Binsen Rong, Ning Zhu, Jindian Duan, Kai Guo

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6 引用 (Scopus)

摘要

The first Pd-catalyzed cyclization of N -aryl-2-aminopyridines with 2-iodobenzoic acids for the synthesis of phenanthridinones through C-H bond activation under very low catalyst loadings (down to 0.1 mol% Pd) in water is reported. This protocol features a broad substrate scope and provides easy efficient access to various phenanthridinones.

源语言英语
文章编号st-2019-l0548-l
页(从-至)280-284
页数5
期刊Synlett
31
3
DOI
出版状态已出版 - 2020

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