摘要
The first organocatalytic enantioselective Michael addition of aldehydes to vinyl sulfones in water was achieved using our rationally designed organocatalyst. The rigid nature of the tricycle with an inherent chiral pocket provides a well-organized chiral environment, which together with the hydrophobic pocket, enabled this elusive reaction to proceed smoothly in water.
| 源语言 | 英语 |
|---|---|
| 页（从-至） | 2029-2032 |
| 页数 | 4 |
| 期刊 | Synlett |
| 期 | 13 |
| DOI | |
| 出版状态 | 已出版 - 2010 |
| 已对外发布 | 是 |