Application of nanosized Fe3O4 in anticancer drug carriers with target-orientation and sustained-release properties

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Abstract

The purpose of this study was to prepare human serum albumin (HSA) microspheres with Fe3O4 magnetic nanoparticles for tumor target therapy. Fe3O4 was obtained by liquid-phase coprecipitation; HSA-coated magnetic particles were attained by solidification at high temperature. The result was that nanosized Fe3O4 is a cubic crystal by XRD and the average size is 18.7 nm; the average size of HSA-coated magnetic particles is 341 nm. Fe3O4 magnetic nanoparticles coated with HSA can be used for targeted-drug carriers with target-orientation and sustained-release properties.

Original languageEnglish
Article number011
Pages (from-to)132-134
Number of pages3
JournalBiomedical Materials (Bristol)
Volume2
Issue number2
DOIs
StatePublished - 1 Jun 2007
Externally publishedYes

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