Application of nanosized Fe₃O₄ in anticancer drug carriers with target-orientation and sustained-release properties

The purpose of this study was to prepare human serum albumin (HSA) microspheres with Fe₃O₄ magnetic nanoparticles for tumor target therapy. Fe₃O₄ was obtained by liquid-phase coprecipitation; HSA-coated magnetic particles were attained by solidification at high temperature. The result was that nanosized Fe₃O₄ is a cubic crystal by XRD and the average size is 18.7 nm; the average size of HSA-coated magnetic particles is 341 nm. Fe₃O₄ magnetic nanoparticles coated with HSA can be used for targeted-drug carriers with target-orientation and sustained-release properties.