Dicyanisophorone-based near-infrared fluorescent probe for the detection of thiophenol and its application in living cells and actual water samples

Guoxing Hu; Zhi Wang; Wenge Yang; Weiliang Shen; Wei Sun; Hanhan Xu; Yonghong Hu

doi:10.1016/j.saa.2022.120984

Dicyanisophorone-based near-infrared fluorescent probe for the detection of thiophenol and its application in living cells and actual water samples

Guoxing Hu, Zhi Wang, Wenge Yang, Weiliang Shen, Wei Sun, Hanhan Xu, Yonghong Hu

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

This article reports a new type of dicyanisophorone-based near-infrared fluorescent probe for the rapid detection of mercaptophenol by introducing 2,4-dinitrobenzene sulfonate group as a specific recognition group for thiophenol. The probe has a significant large Stokes shift (185 nm). At the same time, it exhibits rapid response, high selectivity and high sensitivity to thiophene. In addition, the fluorescence of the probe at 650 nm has a good linear relationship with the concentration of thiophenol in the range of 0–100 μM, and the detection limit is as low as 65 nM. The probe has been successfully applied to the detection of thiophenol in actual water samples, and has good live cell imaging effects, and at the same time shows the superiority of its low cell toxicity.

Original language	English
Article number	120984
Journal	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume	272
DOIs	https://doi.org/10.1016/j.saa.2022.120984
State	Published - 5 May 2022

Keywords

Cell imaging
Dicyanisophorone
Fluorescent probe
Intramolecular charge transfer (ICT)
Thiophenol

Access to Document

10.1016/j.saa.2022.120984

Cite this

@article{9fb1c75c91a3487b8abb8bb25947bca7,

title = "Dicyanisophorone-based near-infrared fluorescent probe for the detection of thiophenol and its application in living cells and actual water samples",

abstract = "This article reports a new type of dicyanisophorone-based near-infrared fluorescent probe for the rapid detection of mercaptophenol by introducing 2,4-dinitrobenzene sulfonate group as a specific recognition group for thiophenol. The probe has a significant large Stokes shift (185 nm). At the same time, it exhibits rapid response, high selectivity and high sensitivity to thiophene. In addition, the fluorescence of the probe at 650 nm has a good linear relationship with the concentration of thiophenol in the range of 0–100 μM, and the detection limit is as low as 65 nM. The probe has been successfully applied to the detection of thiophenol in actual water samples, and has good live cell imaging effects, and at the same time shows the superiority of its low cell toxicity.",

keywords = "Cell imaging, Dicyanisophorone, Fluorescent probe, Intramolecular charge transfer (ICT), Thiophenol",

author = "Guoxing Hu and Zhi Wang and Wenge Yang and Weiliang Shen and Wei Sun and Hanhan Xu and Yonghong Hu",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",

year = "2022",

month = may,

day = "5",

doi = "10.1016/j.saa.2022.120984",

language = "英语",

volume = "272",

journal = "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",

issn = "1386-1425",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Dicyanisophorone-based near-infrared fluorescent probe for the detection of thiophenol and its application in living cells and actual water samples

AU - Hu, Guoxing

AU - Wang, Zhi

AU - Yang, Wenge

AU - Shen, Weiliang

AU - Sun, Wei

AU - Xu, Hanhan

AU - Hu, Yonghong

PY - 2022/5/5

Y1 - 2022/5/5

N2 - This article reports a new type of dicyanisophorone-based near-infrared fluorescent probe for the rapid detection of mercaptophenol by introducing 2,4-dinitrobenzene sulfonate group as a specific recognition group for thiophenol. The probe has a significant large Stokes shift (185 nm). At the same time, it exhibits rapid response, high selectivity and high sensitivity to thiophene. In addition, the fluorescence of the probe at 650 nm has a good linear relationship with the concentration of thiophenol in the range of 0–100 μM, and the detection limit is as low as 65 nM. The probe has been successfully applied to the detection of thiophenol in actual water samples, and has good live cell imaging effects, and at the same time shows the superiority of its low cell toxicity.

AB - This article reports a new type of dicyanisophorone-based near-infrared fluorescent probe for the rapid detection of mercaptophenol by introducing 2,4-dinitrobenzene sulfonate group as a specific recognition group for thiophenol. The probe has a significant large Stokes shift (185 nm). At the same time, it exhibits rapid response, high selectivity and high sensitivity to thiophene. In addition, the fluorescence of the probe at 650 nm has a good linear relationship with the concentration of thiophenol in the range of 0–100 μM, and the detection limit is as low as 65 nM. The probe has been successfully applied to the detection of thiophenol in actual water samples, and has good live cell imaging effects, and at the same time shows the superiority of its low cell toxicity.

KW - Cell imaging

KW - Dicyanisophorone

KW - Fluorescent probe

KW - Intramolecular charge transfer (ICT)

KW - Thiophenol

UR - http://www.scopus.com/inward/record.url?scp=85124326453&partnerID=8YFLogxK

U2 - 10.1016/j.saa.2022.120984

DO - 10.1016/j.saa.2022.120984

M3 - 文章

C2 - 35151172

AN - SCOPUS:85124326453

SN - 1386-1425

VL - 272

JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

M1 - 120984

ER -

Dicyanisophorone-based near-infrared fluorescent probe for the detection of thiophenol and its application in living cells and actual water samples

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this