Electrochemical Synthesis of Alkenylsulfonates from Alkynes, NaHSO3 and Alcohols

Xiaoman Wang; Qianqian Chen; Jinhang Zhou; Yi Hu; Shengqing Ye; Jie Wu

doi:10.1002/cjoc.202400962

Electrochemical Synthesis of Alkenylsulfonates from Alkynes, NaHSO₃ and Alcohols

Xiaoman Wang, Qianqian Chen, Jinhang Zhou, Yi Hu, Shengqing Ye, Jie Wu

School of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Alkenylsulfonates are commonly encountered in medicinal chemistry, polymer chemistry, and organic synthesis. In this research, an electrochemical reaction involving alkynes, NaHSO₃, and alcohols has been developed. This method yields functionalized alkenylsulfonates in good yields with broad functional group tolerance. Mechanism studies indicate that anodic oxidation of inorganic sulfite, radical insertion process, and HAT process are involved in this transformation.

Original language	English
Pages (from-to)	292-296
Number of pages	5
Journal	Chinese Journal of Chemistry
Volume	43
Issue number	3
DOIs	https://doi.org/10.1002/cjoc.202400962
State	Published - 1 Feb 2025

Keywords

Alkenylsulfonates
Alkoxysulfonyl radicals
Alkynes
Electrochemical synthesis
HAT process
Inorganic sulfites

Access to Document

10.1002/cjoc.202400962

Cite this

@article{8ea4d68445a84f43924160b24322b333,

title = "Electrochemical Synthesis of Alkenylsulfonates from Alkynes, NaHSO3 and Alcohols",

abstract = "Alkenylsulfonates are commonly encountered in medicinal chemistry, polymer chemistry, and organic synthesis. In this research, an electrochemical reaction involving alkynes, NaHSO3, and alcohols has been developed. This method yields functionalized alkenylsulfonates in good yields with broad functional group tolerance. Mechanism studies indicate that anodic oxidation of inorganic sulfite, radical insertion process, and HAT process are involved in this transformation.",

keywords = "Alkenylsulfonates, Alkoxysulfonyl radicals, Alkynes, Electrochemical synthesis, HAT process, Inorganic sulfites",

author = "Xiaoman Wang and Qianqian Chen and Jinhang Zhou and Yi Hu and Shengqing Ye and Jie Wu",

note = "Publisher Copyright: {\textcopyright} 2024 SIOC, CAS, Shanghai, & WILEY-VCH GmbH.",

year = "2025",

month = feb,

day = "1",

doi = "10.1002/cjoc.202400962",

language = "英语",

volume = "43",

pages = "292--296",

journal = "Chinese Journal of Chemistry",

issn = "1001-604X",

publisher = "John Wiley and Sons Inc",

number = "3",

}

TY - JOUR

T1 - Electrochemical Synthesis of Alkenylsulfonates from Alkynes, NaHSO3 and Alcohols

AU - Wang, Xiaoman

AU - Chen, Qianqian

AU - Zhou, Jinhang

AU - Hu, Yi

AU - Ye, Shengqing

AU - Wu, Jie

PY - 2025/2/1

Y1 - 2025/2/1

N2 - Alkenylsulfonates are commonly encountered in medicinal chemistry, polymer chemistry, and organic synthesis. In this research, an electrochemical reaction involving alkynes, NaHSO3, and alcohols has been developed. This method yields functionalized alkenylsulfonates in good yields with broad functional group tolerance. Mechanism studies indicate that anodic oxidation of inorganic sulfite, radical insertion process, and HAT process are involved in this transformation.

AB - Alkenylsulfonates are commonly encountered in medicinal chemistry, polymer chemistry, and organic synthesis. In this research, an electrochemical reaction involving alkynes, NaHSO3, and alcohols has been developed. This method yields functionalized alkenylsulfonates in good yields with broad functional group tolerance. Mechanism studies indicate that anodic oxidation of inorganic sulfite, radical insertion process, and HAT process are involved in this transformation.

KW - Alkenylsulfonates

KW - Alkoxysulfonyl radicals

KW - Alkynes

KW - Electrochemical synthesis

KW - HAT process

KW - Inorganic sulfites

UR - http://www.scopus.com/inward/record.url?scp=85208557866&partnerID=8YFLogxK

U2 - 10.1002/cjoc.202400962

DO - 10.1002/cjoc.202400962

M3 - 文章

AN - SCOPUS:85208557866

SN - 1001-604X

VL - 43

SP - 292

EP - 296

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 3

ER -

Electrochemical Synthesis of Alkenylsulfonates from Alkynes, NaHSO₃ and Alcohols

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this