Microwave-assisted synthesis of new spiro[indoline-3,4'-quinoline] derivatives via a one-pot multicomponent reaction

Song Lei Zhu, Kai Zhao, Xiao Ming Su, Shun Jun Ji

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

A simple and efficient synthesis of spiro[indoline-3,4'-quinoline] derivatives by a one-pot reaction of isatin, malononitrile, and enaminone under microwave irradiation was investigated. This protocol has the advantages of short reaction time, high yields of products, broad substrate scope, and easy workup procedure.

Original languageEnglish
Pages (from-to)1355-1366
Number of pages12
JournalSynthetic Communications
Volume39
Issue number8
DOIs
StatePublished - 2009
Externally publishedYes

Keywords

  • Microwave irradiation
  • Multicomponent reactions
  • Spiro[indoline-3,4'- quinoline]

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