Potential industrial application of Actinobacillus succinogenes NJ113 for pyruvic acid production by microaerobic fermentation

Zhen Wang, Wen Xiao, Alie Zhang, Hanxiao Ying, Kequan Chen, Pingkai Ouyang

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Abstract: Actinobacillus succinogenes NJ113 is capable of microaerobic fermentation, which offers the possibility of a novel type of pyruvic acid production. A dissolved oxygen environment with stirring at 300 rpm was a key factor in the fermentative production of a maximum concentration of pyruvic acid. Potassium carbonate (K2CO3) was found to have a role in promoting pyruvic acid production, influencing the concentration of pyruvic acid and production of the by-product succinic acid. The final titer of pyruvic acid production was 36.8±0.1 g L−1 with an overall yield of 0.639±0.056 g g−1 glucose and 3.12±0.03mmol g−1 dry cell weight h−1. Significance and impact of the study: This study is the first to illustrate the advantage of using Actinobacillus succinogenes NJ113 with no genetic modification under microaerobic conditions for the production of pyruvic acid.

Original languageEnglish
Pages (from-to)2908-2914
Number of pages7
JournalKorean Journal of Chemical Engineering
Volume33
Issue number10
DOIs
StatePublished - 1 Oct 2016

Keywords

  • Actinobacillus succinogenes
  • Dissolved Oxygen Environment
  • Microaerobic Fermentation
  • Potassium Carbonate
  • Pyruvic Acid

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