Potential industrial application of Actinobacillus succinogenes NJ113 for pyruvic acid production by microaerobic fermentation

Zhen Wang, Wen Xiao, Alie Zhang, Hanxiao Ying, Kequan Chen, Pingkai Ouyang

科研成果: 期刊稿件文章同行评审

11 引用 (Scopus)

摘要

Abstract: Actinobacillus succinogenes NJ113 is capable of microaerobic fermentation, which offers the possibility of a novel type of pyruvic acid production. A dissolved oxygen environment with stirring at 300 rpm was a key factor in the fermentative production of a maximum concentration of pyruvic acid. Potassium carbonate (K2CO3) was found to have a role in promoting pyruvic acid production, influencing the concentration of pyruvic acid and production of the by-product succinic acid. The final titer of pyruvic acid production was 36.8±0.1 g L−1 with an overall yield of 0.639±0.056 g g−1 glucose and 3.12±0.03mmol g−1 dry cell weight h−1. Significance and impact of the study: This study is the first to illustrate the advantage of using Actinobacillus succinogenes NJ113 with no genetic modification under microaerobic conditions for the production of pyruvic acid.

源语言英语
页(从-至)2908-2914
页数7
期刊Korean Journal of Chemical Engineering
33
10
DOI
出版状态已出版 - 1 10月 2016

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