Synthesis and bioactivity of novel 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl) acetamides

Peng Yu; Xi Li; Xiao Zhang; Yanhua Xu

doi:10.24820/ARK.5550190.P011.091

Synthesis and bioactivity of novel 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl) acetamides

Peng Yu, Xi Li, Xiao Zhang, Yanhua Xu

School of Environmental Science and Engineering

Nanjing Tech University

Research output: Contribution to journal › Article › peer-review

Abstract

Nine novel types of 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl)-acetamides were synthesized, and their inhibition effects on selected bacteria (heterotrophic bacteria) and algae (marine chlorella) were evaluated. Results showed that 2-(1,2-benzisothiazol-3-yloxy)-N-(3-cyano-1-(2,4-dimethylphenyl)pyrazol-5-yl) acetamide achieved the highest yield of 81% with good bioactivity against heterotrophic bacteria and marine chlorella.

Original language	English
Pages (from-to)	397-405
Number of pages	9
Journal	Arkivoc
Volume	2019
Issue number	6
DOIs	https://doi.org/10.24820/ARK.5550190.P011.091
State	Published - Jan 2020

Keywords

Bioactivity
Isothiazolinone
N-Aryl pyrazole
Synthesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.24820/ARK.5550190.P011.091

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title = "Synthesis and bioactivity of novel 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl) acetamides",

abstract = "Nine novel types of 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl)-acetamides were synthesized, and their inhibition effects on selected bacteria (heterotrophic bacteria) and algae (marine chlorella) were evaluated. Results showed that 2-(1,2-benzisothiazol-3-yloxy)-N-(3-cyano-1-(2,4-dimethylphenyl)pyrazol-5-yl) acetamide achieved the highest yield of 81% with good bioactivity against heterotrophic bacteria and marine chlorella.",

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author = "Peng Yu and Xi Li and Xiao Zhang and Yanhua Xu",

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T1 - Synthesis and bioactivity of novel 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl) acetamides

AU - Yu, Peng

AU - Li, Xi

AU - Zhang, Xiao

AU - Xu, Yanhua

N1 - Publisher Copyright: © AUTHOR (S).

PY - 2020/1

Y1 - 2020/1

N2 - Nine novel types of 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl)-acetamides were synthesized, and their inhibition effects on selected bacteria (heterotrophic bacteria) and algae (marine chlorella) were evaluated. Results showed that 2-(1,2-benzisothiazol-3-yloxy)-N-(3-cyano-1-(2,4-dimethylphenyl)pyrazol-5-yl) acetamide achieved the highest yield of 81% with good bioactivity against heterotrophic bacteria and marine chlorella.

AB - Nine novel types of 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl)-acetamides were synthesized, and their inhibition effects on selected bacteria (heterotrophic bacteria) and algae (marine chlorella) were evaluated. Results showed that 2-(1,2-benzisothiazol-3-yloxy)-N-(3-cyano-1-(2,4-dimethylphenyl)pyrazol-5-yl) acetamide achieved the highest yield of 81% with good bioactivity against heterotrophic bacteria and marine chlorella.

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KW - Isothiazolinone

KW - N-Aryl pyrazole

KW - Synthesis

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M3 - 文章

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SN - 1551-7004

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ER -

Synthesis and bioactivity of novel 2-(1,2-benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl) acetamides

Abstract

Keywords

UN SDGs

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