β-C(sp3)-H Arylation of α-Hydroxy Acid Derivatives Utilizing Amino Acid as a Directing Group

Tetsuya Toba, Yi Hu, Anh T. Tran, Jin Quan Yu

科研成果: 期刊稿件文章同行评审

29 引用 (Scopus)

摘要

The Pd(II)-catalyzed arylation of unactivated β-C(sp3)-H bonds in α-hydroxy aliphatic acid with a variety of aryl iodides was developed utilizing an amino acid auxiliary as a directing group. This protocol provides access to biologically active β-arylated-α-hydroxy acid derivatives.

源语言英语
页(从-至)5966-5969
页数4
期刊Organic Letters
17
24
DOI
出版状态已出版 - 4 12月 2015

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